Treatment Efficacy, ε = reduction in GA lesion area growth compared to a control group

For reference:

OAKS & DERBY ε = 26% for pegcetacoplan monthly, ε = 22% for pegcetacoplan EOM

GALE (extrafoveal) ε = 32% for pegcetacoplan monthly, ε = 26% for pegcetacoplan EOM

GATHER 1 ε = 35.4% for avacincaptad pegol (ACP)

GATHER 2 ε = 17.7% for avacincaptad pegol (ACP)

Calculator created for research purposes only. All clinical decisions should be made with a retina specialist taking into account clinical history, exam, activities of daily living, and imaging.

Calculator created by Casey Zhang, MD and Ravi Parikh, MD MPH

For further correspondence, please reach out to Dr. Ravi Parikh, MD MPH (rap120@mail.harvard.edu).